USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P08758 USC-OGP 2-DE database:  P08758 P08758 General information about the entry View entry in simple text format Entry name ANXA5_HUMAN Primary accession number P08758 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Annexin A5; AltName: Full=Anchorin CII; AltName: Full=Annexin V; AltName: Full=Annexin-5; AltName: Full=Calphobindin I; Short=CBP-I; AltName: Full=Endonexin II; AltName: Full=Lipocortin V; AltName: Full=Placental anticoagulant protein 4; Short=PP4; AltName: Full=Placental anticoagulant protein I; Short=PAP-I; AltName: Full=Thromboplastin inhibitor; AltName: Full=Vascular anticoagulant-alpha; Short=VAC-alpha;. Gene name Name=ANXA5 Synonyms=ANX5, ENX2, PP4 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0139: pI=4.93; Mw=32668 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1235: pI=5.27; Mw=33325 SPOT OGP-1237: pI=4.73; Mw=33231 SPOT OGP-1240: pI=5.05; Mw=32400 SPOT OGP-1241: pI=4.42; Mw=32219 SPOT OGP-1249: pI=6.60; Mw=31413 Cross-references UniProtKB/Swiss-Prot P08758; ANXA5_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name ANXA5_HUMAN Primary accession number P08758 Secondary accession number(s) D3DNW7 Q6FHB3 Q6FI16 Q8WV69 Q9UDH9 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 197) Name and origin of the protein Description RecName: Full=Annexin A5; AltName: Full=Anchorin CII; AltName: Full=Annexin V; AltName: Full=Annexin-5; AltName: Full=Calphobindin I; Short=CBP-I; AltName: Full=Endonexin II; AltName: Full=Lipocortin V; AltName: Full=Placental anticoagulant protein 4; Short=PP4; AltName: Full=Placental anticoagulant protein I; Short=PAP-I; AltName: Full=Thromboplastin inhibitor; AltName: Full=Vascular anticoagulant-alpha; Short=VAC-alpha; Gene name Name=ANXA5 Synonyms=ANX5, ENX2, PP4 Encoded on Name=ANXA5; Synonyms=ANX5, ENX2, PP4 Keywords 3D-structure; Acetylation; Annexin; Blood coagulation; Calcium; Calcium/phospholipid-binding; Complete proteome; Direct protein sequencing; Hemostasis; Isopeptide bond; Phosphoprotein; Reference proteome; Repeat; S-nitrosylation; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M18366; AAA35570.1; -; mRNA EMBL D00172; BAA00122.1; -; mRNA EMBL X12454; CAA30985.1; -; mRNA EMBL J03745; AAA52386.1; -; mRNA EMBL M21731; AAA36166.1; -; mRNA EMBL M19384; AAB59545.1; -; mRNA EMBL U01691; AAB40047.1; -; Genomic_DNA EMBL U01681; AAB40047.1; JOINED; Genomic_DNA EMBL U01682; AAB40047.1; JOINED; Genomic_DNA EMBL U01683; AAB40047.1; JOINED; Genomic_DNA EMBL U01685; AAB40047.1; JOINED; Genomic_DNA EMBL U01686; AAB40047.1; JOINED; Genomic_DNA EMBL U01687; AAB40047.1; JOINED; Genomic_DNA EMBL U01689; AAB40047.1; JOINED; Genomic_DNA EMBL U01690; AAB40047.1; JOINED; Genomic_DNA EMBL U05770; AAB60648.1; -; Genomic_DNA EMBL U05760; AAB60648.1; JOINED; Genomic_DNA EMBL U05761; AAB60648.1; JOINED; Genomic_DNA EMBL U05762; AAB60648.1; JOINED; Genomic_DNA EMBL U05764; AAB60648.1; JOINED; Genomic_DNA EMBL U05765; AAB60648.1; JOINED; Genomic_DNA EMBL U05766; AAB60648.1; JOINED; Genomic_DNA EMBL U05767; AAB60648.1; JOINED; Genomic_DNA EMBL U05768; AAB60648.1; JOINED; Genomic_DNA EMBL U05769; AAB60648.1; JOINED; Genomic_DNA EMBL AK312644; BAG35528.1; -; mRNA EMBL CR536522; CAG38759.1; -; mRNA EMBL CR541842; CAG46640.1; -; mRNA EMBL AC096730; AAY40954.1; -; Genomic_DNA EMBL CH471056; EAX05257.1; -; Genomic_DNA EMBL CH471056; EAX05258.1; -; Genomic_DNA EMBL BC001429; AAH01429.1; -; mRNA EMBL BC004993; AAH04993.1; -; mRNA EMBL BC012804; AAH12804.1; -; mRNA EMBL BC012822; AAH12822.1; -; mRNA EMBL BC018671; AAH18671.1; -; mRNA CCDS CCDS3720.1; -; . PIR D29250; AQHUP; . RefSeq NP_001145.1; NM_001154.3; . UniGene Hs.480653; -; . PDB 1ANW; X-ray; 2.40 A; A/B=2-320 PDB 1ANX; X-ray; 1.90 A; A/B/C=2-320 PDB 1AVH; X-ray; 2.30 A; A/B=1-320 PDB 1AVR; X-ray; 2.30 A; A=1-320 PDB 1HAK; X-ray; 3.00 A; A/B=1-320 PDB 1HVD; X-ray; 2.00 A; A=2-320 PDB 1HVE; X-ray; 2.30 A; A=2-320 PDB 1HVF; X-ray; 2.00 A; A=2-320 PDB 1HVG; X-ray; 3.00 A; A=2-320 PDB 1SAV; X-ray; 2.50 A; A=1-320 PDB 2XO2; X-ray; 2.80 A; A=1-320 PDB 2XO3; X-ray; 2.30 A; A=1-320 PDBsum 1ANW; -; . PDBsum 1ANX; -; . PDBsum 1AVH; -; . PDBsum 1AVR; -; . PDBsum 1HAK; -; . PDBsum 1HVD; -; . PDBsum 1HVE; -; . PDBsum 1HVF; -; . PDBsum 1HVG; -; . PDBsum 1SAV; -; . PDBsum 2XO2; -; . PDBsum 2XO3; -; . ProteinModelPortal P08758; -; . SMR P08758; -; . BioGrid 106805; 42; . IntAct P08758; 21; . MINT MINT-1382250; -; . STRING 9606.ENSP00000296511; -; . DrugBank DB02929; K201; . DrugBank DB03484; L-Alpha-Glycerophosphorylethanolamine; . DrugBank DB02497; L-Alpha-Glycerophosphorylserine; . DrugBank DB02846; L-thioproline; . TCDB 1.A.31.1.7; the annexin (annexin) family; . iPTMnet P08758; -; . PhosphoSitePlus P08758; -; . SwissPalm P08758; -; . BioMuta ANXA5; -; . DMDM 113960; -; . OGP P08758; -; . REPRODUCTION-2DPAGE IPI00329801; -; . REPRODUCTION-2DPAGE P08758; -; . EPD P08758; -; . PaxDb P08758; -; . PeptideAtlas P08758; -; . PRIDE P08758; -; . TopDownProteomics P08758; -; . DNASU 308; -; . Ensembl ENST00000296511; ENSP00000296511; ENSG00000164111; . GeneID 308; -; . KEGG hsa:308; -; . CTD 308; -; . DisGeNET 308; -; . GeneCards ANXA5; -; . HGNC HGNC:543; ANXA5; . HPA CAB003677; -; . HPA HPA035330; -; . MalaCards ANXA5; -; . MIM 131230; gene; . MIM 614391; phenotype; . neXtProt NX_P08758; -; . OpenTargets ENSG00000164111; -; . PharmGKB PA24833; -; . eggNOG KOG0819; Eukaryota; . eggNOG ENOG410XPUN; LUCA; . GeneTree ENSGT00760000118972; -; . HOGENOM HOG000158803; -; . HOVERGEN HBG061815; -; . InParanoid P08758; -; . KO K16646; -; . OMA IRHEFRK; -; . OrthoDB EOG091G0H6H; -; . PhylomeDB P08758; -; . TreeFam TF105452; -; . Reactome R-HSA-114608; Platelet degranulation; . SignaLink P08758; -; . ChiTaRS ANXA5; human; . EvolutionaryTrace P08758; -; . GeneWiki Annexin_A5; -; . GenomeRNAi 308; -; . PRO PR:P08758; -; . Proteomes UP000005640; Chromosome 4; . Bgee ENSG00000164111; -; . CleanEx HS_ANXA5; -; . ExpressionAtlas P08758; baseline and differential; . Genevisible P08758; HS; . GO GO:0005737; C:cytoplasm; TAS:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0072563; C:endothelial microparticle; IEA:Ensembl; . GO GO:0009897; C:external side of plasma membrane; IEA:Ensembl; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0005622; C:intracellular; IDA:LIFEdb; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005509; F:calcium ion binding; IEA:InterPro; . GO GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB; . GO GO:0004859; F:phospholipase inhibitor activity; TAS:ProtInc; . GO GO:0005543; F:phospholipid binding; TAS:ProtInc; . GO GO:0007596; P:blood coagulation; IEA:UniProtKB-KW; . GO GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB; . GO GO:0050819; P:negative regulation of coagulation; IEA:InterPro; . GO GO:0002576; P:platelet degranulation; TAS:Reactome; . GO GO:0010033; P:response to organic substance; IEA:Ensembl; . GO GO:0007165; P:signal transduction; TAS:UniProtKB; . Gene3D 1.10.220.10; -; 4; . InterPro IPR001464; Annexin; . InterPro IPR018502; Annexin_repeat; . InterPro IPR018252; Annexin_repeat_CS; . InterPro IPR002392; ANX5; . PANTHER PTHR10502:SF140; PTHR10502:SF140; 1; . Pfam PF00191; Annexin; 4; . PRINTS PR00196; ANNEXIN; . PRINTS PR00201; ANNEXINV; . SMART SM00335; ANX; 4; . PROSITE PS00223; ANNEXIN; 4; .

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